{"product_id":"nsc-617145-e0422","title":"NSC 617145","description":"\u003cp\u003e\u003cstrong\u003eNSC 617145\u003c\/strong\u003e is an inhibitor of ATPases used in studies of DNA Damage Response. It is especially relevant in cancer, cell signaling, and dna damage \/ repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting ATPases, NSC 617145 can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving ATPases\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, NSC 617145 is appropriate when a defined chemical perturbant is needed to connect ATPases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804253397337,"sku":"E0422-5MG","price":2670.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804253430105,"sku":"E0422-25MG","price":8008.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E0422-NSC-617145-chemical-structure.png?v=1776166012","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/nsc-617145-e0422","provider":"Absource Diagnostics","version":"1.0","type":"link"}