{"product_id":"nkcc2-slc12a1-human-antibody-western-blot-validated","title":"NKCC2 (Slc12a1) (Human) Antibody - Western Blot Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eThis antibody supports efforts to examine NKCC2 and interpret it within interaction networks. NKCC2 is a membrane-embedded regulator of ionic or osmotic balance in cells. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eTracking NKCC2 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eMany transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eDepending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esurface versus intracellular pool distribution\u003c\/li\u003e\n\u003cli\u003erelative abundance across engineered constructs\u003c\/li\u003e\n\u003cli\u003epatterns consistent with apical or basolateral sorting\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eIf your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for NKCC2 so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting NKCC2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eUse the denaturing-format version to relate NKCC2 behavior to upstream cues and downstream consequences.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101792047449,"sku":"20301H-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101792080217,"sku":"20301H-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101792112985,"sku":"20301H-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101792145753,"sku":"20301H-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101792178521,"sku":"20301H-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101792211289,"sku":"20301H-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/nkcc2.jpg?v=1779281580","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/nkcc2-slc12a1-human-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}