{"product_id":"nkcc2-slc12a1-antibody-western-blot-validated","title":"NKCC2 (Slc12a1) Antibody - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003eBuild reproducible readouts by using this antibody to characterize NKCC2 (Slc12a1) across matched sample sets. NKCC2 is a membrane-embedded regulator of ionic or osmotic balance in cells. For comparison-heavy studies, consistent sample handling and normalization help reduce run-to-run drift.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol Slc12a1.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eModulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows.\u003c\/p\u003e\n\u003cp\u003eTarget-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing. Kidney-focused model systems may monitor this target when evaluating transport, barrier features, or compartment identity.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003epatterns consistent with apical or basolateral sorting\u003c\/li\u003e\n\u003cli\u003estimulus-dependent trafficking and turnover\u003c\/li\u003e\n\u003cli\u003esurface versus intracellular pool distribution\u003c\/li\u003e\n\u003cli\u003erelative abundance across engineered constructs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eWhen samples are prepared in reducing conditions, some epitopes become more accessible; this version is designed with that context in mind. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Document normalization choices so collaborators can reproduce the same interpretation.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing NKCC2 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eWith consistent handling, the denaturing-format format can make NKCC2 (Slc12a1) comparisons easier to reproduce across runs.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101792964953,"sku":"20301-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101792997721,"sku":"20301-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101793030489,"sku":"20301-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101793063257,"sku":"20301-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101793096025,"sku":"20301-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101793128793,"sku":"20301-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/nkcc2-kid.jpg?v=1779281585","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/nkcc2-slc12a1-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}