{"product_id":"niclosamide-ethanolamine-e6051","title":"niclosamide ethanolamine","description":"\u003cp\u003e\u003cstrong\u003eniclosamide ethanolamine\u003c\/strong\u003e is an inhibitor of STAT used in studies of PI3K-Akt-mTOR Signaling and JAK-STAT Signaling and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-responsive transcriptional signaling and immune regulation in apoptosis, autophagy, and cancer models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting STAT, niclosamide ethanolamine can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and cytokine-responsive transcriptional signaling and immune regulation. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving STAT\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and JAK-STAT Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, niclosamide ethanolamine is appropriate when a defined chemical perturbant is needed to connect STAT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"100 mg","offer_id":57805015286105,"sku":"E6051-100MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805015318873,"sku":"E6051-1G","price":776.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E6051-niclosamide-ethanolamine-chemical-structure.png?v=1776170721","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/niclosamide-ethanolamine-e6051","provider":"Absource Diagnostics","version":"1.0","type":"link"}