{"product_id":"neurod1-antibody-sc-f1690","title":"NeuroD1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eNeurogenic differentiation 1 (NeuroD1\/β2), is a member of the basic helix-loop-helix (bHLH) family of transcription factors that regulate endocrine and neuronal cell differentiation. It is expressed in pancreatic and neuronal cells. NeuroD1 binds to specific DNA sequences and triggers the transcription of genes important for glucose homeostasis, such as INS, SUR1, GCK, and PAX6.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm and nucleus, which can matter when signal is compared across treatments or changing cell states. Following NEUROD1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eNEUROD1 is commonly interpreted in the context of neuroscience and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for NEUROD1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in NEUROD1 reflect biology rather than handling. When interpreting NEUROD1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep NEUROD1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577820356953,"sku":"F1690-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577820389721,"sku":"F1690-100UL","price":369.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577820422489,"sku":"F1690-2X100UL","price":549.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1690-IHC1.jpg?v=1773600029","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/neurod1-antibody-sc-f1690","provider":"Absource Diagnostics","version":"1.0","type":"link"}