{"product_id":"ndrg2-antibody-sc-f3171","title":"NDRG2 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eN-myc downstream-regulated gene 2 (NDRG2) is a cytoplasmic protein highly expressed in the brain, kidney, skeletal muscle, and other tissues, playing a crucial role in cellular stress response, metabolism, and tumor suppression. It regulates neuroprotection, astrocyte activation, and synaptic plasticity, with implications for psychiatric disorders like depression and ADHD.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell projection and cytoplasm, which can matter when signal is compared across treatments or changing cell states. Following NDRG2 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eNDRG2 is commonly interpreted in the context of cancer, neuroscience, and metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell projection and cytoplasm, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell projection and cytoplasm across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for NDRG2. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in NDRG2 reflect biology rather than handling. When interpreting NDRG2, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep NDRG2 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578006511961,"sku":"F3171-20UL","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578006544729,"sku":"F3171-100UL","price":299.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578006577497,"sku":"F3171-2X100UL","price":479.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3171-wb.gif?v=1773600980","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ndrg2-antibody-sc-f3171","provider":"Absource Diagnostics","version":"1.0","type":"link"}