{"product_id":"ndrg1-antibody-sc-f0739","title":"NDRG1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eNDRG1 belongs to the NDRG family, alongside NDRG2, NDRG3, and NDRG4. While NDRG1 shows robust expression in the cerebral cortex, the other family members are also present in the spinal cord during developmental stages, where they contribute to central nervous system differentiation. The levels of NDRG1 mRNA vary across human tissues, with particularly high expression in the prostate, brain, kidney, placenta, and intestinal tissues.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, cytoplasm, cytoskeleton, and membrane, which can matter when signal is compared across treatments or changing cell states. Following NDRG1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eNDRG1 is commonly interpreted in the context of cancer and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cytoplasm, and cytoskeleton, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, cytoplasm, and cytoskeleton across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for NDRG1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in NDRG1 reflect biology rather than handling. When interpreting NDRG1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep NDRG1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577510732121,"sku":"F0739-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577510764889,"sku":"F0739-100UL","price":359.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577510797657,"sku":"F0739-2X100UL","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0739-IHC1.jpg?v=1773598863","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ndrg1-antibody-sc-f0739","provider":"Absource Diagnostics","version":"1.0","type":"link"}