{"product_id":"ncc-slc12a3-mouse-antibody-ffpe-validated","title":"NCC (SLC12a3) (mouse) Antibody - FFPE Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eUse this antibody to characterize NCC (SLC12a3) when mapping complex behavior and signaling context. NCC is a membrane protein linked to solute movement and gradient maintenance. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol SLC12a3.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eModulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eSince many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes. Kidney-focused model systems may monitor this target when evaluating transport, barrier features, or compartment identity.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003estimulus-dependent trafficking and turnover\u003c\/li\u003e\n\u003cli\u003esurface versus intracellular pool distribution\u003c\/li\u003e\n\u003cli\u003erelative abundance across engineered constructs\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eBecause fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting NCC, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eThe fixed-section option supports mechanistic reading of NCC (SLC12a3) when interactions and context are the focus.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101787132249,"sku":"20303M-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101787165017,"sku":"20303M-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101787197785,"sku":"20303M-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101787230553,"sku":"20303M-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101787263321,"sku":"20303M-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101787296089,"sku":"20303M-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/nccmpendrin_798c7bb6-c3e9-45e4-afe9-1d8bdb02dfd0.jpg?v=1779281549","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ncc-slc12a3-mouse-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}