{"product_id":"muscone-s3871","title":"Muscone","description":"\u003cp\u003e\u003cstrong\u003eMuscone\u003c\/strong\u003e is an inhibitor of NF-kB and NLRP3 and related targets used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling in immunology and inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting NF-kB and NLRP3 and related targets, Muscone can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In immunology and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving NF-kB and NLRP3 and related targets\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eImmune-cell activation, cytokine, and mediator assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Muscone is appropriate when a defined chemical perturbant is needed to connect NF-kB and NLRP3 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in immunology and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"25 mg","offer_id":57808967401817,"sku":"S3871-25MG","price":88.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57808967434585,"sku":"S3871-1G","price":481.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/muscone-chemical-structure-s3871.gif?v=1776195561","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/muscone-s3871","provider":"Absource Diagnostics","version":"1.0","type":"link"}