{"product_id":"ml-60218-e6515","title":"ML-60218","description":"\u003cp\u003e\u003cstrong\u003eML-60218\u003c\/strong\u003e is an inhibitor of DNA\/RNA Synthesis used in studies of DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control in cancer and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting DNA\/RNA Synthesis, ML-60218 can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DNA\/RNA Synthesis\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, ML-60218 is appropriate when a defined chemical perturbant is needed to connect DNA\/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57805026459993,"sku":"E6515-1MG","price":194.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57805026492761,"sku":"E6515-5MG","price":284.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805026525529,"sku":"E6515-25MG","price":764.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805026558297,"sku":"E6515-100MG","price":1740.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E6515-ML-60218-chemical-structure.png?v=1776170876","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ml-60218-e6515","provider":"Absource Diagnostics","version":"1.0","type":"link"}