{"product_id":"mks3-nphp11-or-meckelin-or-tmem67-xenopus-antibody-western-blot-validated","title":"MKS3 (NPHP11 or Meckelin or TMEM67) (Xenopus) Antibody - Western Blot Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eThis antibody supports experimental designs that evaluate MKS3 (NPHP11) with interpretable controls and clear contrasts. MKS3 is a trafficking-related component that can localize to basal bodies and ciliary axonemes. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol NPHP11.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eCiliary proteins are frequently assessed in relation to cell-cycle stage, serum conditions, and differentiation cues. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eBecause cellular networks are interconnected, changes in this target may coincide with shifts in related pathways, trafficking behavior, or structural remodeling.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003ecell-cycle linked differences in localization\u003c\/li\u003e\n\u003cli\u003echanges in cilia incidence or apparent length in perturbation studies\u003c\/li\u003e\n\u003cli\u003esignal enrichment at basal bodies versus cytoplasm\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eIf your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. Align controls to the expected direction of change to support confident interpretation.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing MKS3 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eUse the denaturing-format option to keep MKS3 (NPHP11) analysis aligned with planned contrasts and endpoints.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101371928921,"sku":"90103X-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101371961689,"sku":"90103X-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101371994457,"sku":"90103X-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101372027225,"sku":"90103X-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101372059993,"sku":"90103X-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101372092761,"sku":"90103X-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mks-xenopus.jpg?v=1779279416","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/mks3-nphp11-or-meckelin-or-tmem67-xenopus-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}