{"product_id":"mizagliflozin-kwa-0711-dsp-3235-free-base-s8939","title":"Mizagliflozin (KWA 0711, DSP-3235 free base)","description":"\u003cp\u003e\u003cstrong\u003eMizagliflozin (KWA 0711, DSP-3235 free base)\u003c\/strong\u003e is an inhibitor of SGLT1 and SGLT used in studies of GPCR Signaling and Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting SGLT1 and SGLT, Mizagliflozin (KWA 0711, DSP-3235 free base) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake\/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving SGLT1 and SGLT\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eTransport, uptake\/efflux, and permeability assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Mizagliflozin (KWA 0711, DSP-3235 free base) is appropriate when a defined chemical perturbant is needed to connect SGLT1 and SGLT with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809672143193,"sku":"S8939-5MG","price":265.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809672175961,"sku":"S8939-25MG","price":881.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57809672208729,"sku":"S8939-100MG","price":1936.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57809672241497,"sku":"S8939-1G","price":4904.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809672274265,"sku":"S8939-1ML\/DMSO","price":342.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/mizagliflozin-chemical-structure-s8939.gif?v=1776204835","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/mizagliflozin-kwa-0711-dsp-3235-free-base-s8939","provider":"Absource Diagnostics","version":"1.0","type":"link"}