{"product_id":"metformin-hydrochloride-s1950","title":"Metformin Hydrochloride","description":"\u003cp\u003e\u003cstrong\u003eMetformin Hydrochloride\u003c\/strong\u003e is a research compound associated with AMPK and is relevant to studies of PI3K-Akt-mTOR Signaling and MAPK \/ ERK Signaling and related signaling programs. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in apoptosis, autophagy, and cancer models.\u003c\/p\u003e\n\n\u003cp\u003eThe current annotation links Metformin Hydrochloride to AMPK, supporting target-focused studies that measure growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling without assigning a more specific primary mechanism than the dataset provides. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, autophagy, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving AMPK\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK \/ ERK Signaling and related signaling programs\u003c\/li\u003e\n\u003cli\u003eMetabolite supplementation and biochemical reference studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Metformin Hydrochloride is appropriate when a defined chemical perturbant is needed to connect AMPK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, autophagy, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"500 mg","offer_id":57805377700185,"sku":"S1950-500MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805377732953,"sku":"S1950-1G","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"5 g","offer_id":57805377765721,"sku":"S1950-5G","price":390.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Metformin-hydrochloride-Glucophage-chemical-structure-S1950.gif?v=1776174247","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/metformin-hydrochloride-s1950","provider":"Absource Diagnostics","version":"1.0","type":"link"}