{"product_id":"mercaptopurine-6-mp-s1305","title":"Mercaptopurine (6-MP)","description":"\u003cp\u003e\u003cstrong\u003eMercaptopurine (6-MP)\u003c\/strong\u003e is an inhibitor of DNA\/RNA Synthesis and Transferases used in studies of DNA Damage Response and Metabolic Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control and metabolic regulation, energy sensing, and enzyme-linked homeostasis in cancer, dna damage \/ repair, and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting DNA\/RNA Synthesis and Transferases, Mercaptopurine (6-MP) can be used to examine checkpoint activation, DNA repair, and genome-stability control and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage \/ repair, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DNA\/RNA Synthesis and Transferases\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Mercaptopurine (6-MP) is appropriate when a defined chemical perturbant is needed to connect DNA\/RNA Synthesis and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage \/ repair, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805266977113,"sku":"S1305-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805267009881,"sku":"S1305-1G","price":658.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805267042649,"sku":"S1305-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Mercaptopurine-chemical-structure-S1305.gif?v=1776173314","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/mercaptopurine-6-mp-s1305","provider":"Absource Diagnostics","version":"1.0","type":"link"}