{"product_id":"megestrol-s5738","title":"Megestrol","description":"\u003cp\u003e\u003cstrong\u003eMegestrol\u003c\/strong\u003e is a modulator of Estrogen\/Progesterone Receptors used in studies of Hormone Signaling. It is especially relevant in endocrinology models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating Estrogen\/Progesterone Receptors, Megestrol can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Estrogen\/Progesterone Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Hormone Signaling\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Megestrol is appropriate when a defined chemical perturbant is needed to connect Estrogen\/Progesterone Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"25 mg","offer_id":57809276830041,"sku":"S5738-25MG","price":95.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s5738-megestrol-chemical-structure.gif?v=1776198771","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/megestrol-s5738","provider":"Absource Diagnostics","version":"1.0","type":"link"}