{"product_id":"mcp1-antibody-sc-f3225","title":"MCP1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eMCP1 is a target of interest in many antibody-based workflows. Monocyte chemoattractant protein-1 (MCP-1\/CCL2) is a member of the C-C chemokine family and functions as a potent chemotactic factor for monocytes. It is considered identical to JE, a gene originally identified in mouse fibroblasts as being induced by platelet-derived growth factor. The human MCP-1 gene is located on chromosome 17q11. Depending on the literature source, MCP1 may also be discussed as Je and Scya2.\u003c\/p\u003e\u003cp\u003eReported cellular context includes secreted, which can matter when signal is compared across treatments or changing cell states. Following MCP1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eMCP1 is commonly interpreted in the context of immunology, neuroscience, and infectious disease research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans secreted, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within secreted relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003ehost-response changes during infection or pathogen-associated stimulation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for MCP1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in MCP1 reflect biology rather than handling. When interpreting MCP1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep MCP1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578010181977,"sku":"F3225-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578010214745,"sku":"F3225-100UL","price":359.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578010247513,"sku":"F3225-2X100UL","price":539.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3225-IHC1.jpg?v=1773601038","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/mcp1-antibody-sc-f3225","provider":"Absource Diagnostics","version":"1.0","type":"link"}