{"product_id":"m2912-e1069","title":"M2912","description":"\u003cp\u003e\u003cstrong\u003eM2912\u003c\/strong\u003e is an inhibitor of PARP and Wnt \/ beta-catenin used in studies of Wnt Signaling and DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control in cancer, cell signaling, and developmental biology models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting PARP and Wnt \/ beta-catenin, M2912 can be used to examine beta-catenin-dependent transcription and developmental signaling and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving PARP and Wnt \/ beta-catenin\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Wnt Signaling and DNA Damage Response\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, M2912 is appropriate when a defined chemical perturbant is needed to connect PARP and Wnt \/ beta-catenin with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804321161561,"sku":"E1069-5MG","price":215.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804321194329,"sku":"E1069-25MG","price":645.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1069-m2912-chemical-structure.png?v=1776166460","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/m2912-e1069","provider":"Absource Diagnostics","version":"1.0","type":"link"}