{"product_id":"ly-3381916-s8919","title":"LY-3381916","description":"\u003cp\u003e\u003cstrong\u003eLY-3381916\u003c\/strong\u003e is an inhibitor of IDO1 and TDO used in studies of Immune Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses in cancer, immunology, and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting IDO1 and TDO, LY-3381916 can be used to examine cytokine-mediated signaling and inflammatory effector responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, immunology, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving IDO1 and TDO\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, LY-3381916 is appropriate when a defined chemical perturbant is needed to connect IDO1 and TDO with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809667686745,"sku":"S8919-5MG","price":146.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809667719513,"sku":"S8919-25MG","price":439.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s8919-ly-3381916-chemical-structure.gif?v=1776204823","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ly-3381916-s8919","provider":"Absource Diagnostics","version":"1.0","type":"link"}