{"product_id":"lovastatin-mevinolin-mk-803-s2061","title":"Lovastatin (Mevinolin, MK-803)","description":"\u003cp\u003e\u003cstrong\u003eLovastatin (Mevinolin, MK-803)\u003c\/strong\u003e is an inhibitor of HMG-CoA Reductase used in studies of Autophagy and Metabolic Signaling. It is especially relevant in autophagy, cardiovascular, and metabolism models, where defined compound exposure can be linked to autophagic flux, lysosomal turnover, and stress adaptation and metabolic regulation, energy sensing, and enzyme-linked homeostasis.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting HMG-CoA Reductase, Lovastatin (Mevinolin, MK-803) can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cardiovascular, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving HMG-CoA Reductase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Autophagy and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Lovastatin (Mevinolin, MK-803) is appropriate when a defined chemical perturbant is needed to connect HMG-CoA Reductase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cardiovascular, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"50 mg","offer_id":57805400342873,"sku":"S2061-50MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"200 mg","offer_id":57805400375641,"sku":"S2061-200MG","price":265.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805400408409,"sku":"S2061-1G","price":579.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805400441177,"sku":"S2061-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s2061-lovastatin-mk-803-chemical-structure.png?v=1776174426","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/lovastatin-mevinolin-mk-803-s2061","provider":"Absource Diagnostics","version":"1.0","type":"link"}