{"product_id":"lometrexol-e1766","title":"Lometrexol","description":"\u003cp\u003e\u003cstrong\u003eLometrexol\u003c\/strong\u003e is an inhibitor of Histone Methyltransferases and Transferases used in studies of Apoptosis and Epigenetic Regulation and related signaling programs. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation in apoptosis, cancer, and cell cycle models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Histone Methyltransferases and Transferases, Lometrexol can be used to examine caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Histone Methyltransferases and Transferases\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Epigenetic Regulation and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Lometrexol is appropriate when a defined chemical perturbant is needed to connect Histone Methyltransferases and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Default Title","offer_id":57818427720025,"sku":"E1766","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1766-lometrexol-chemical-structure-tube.png?v=1776275092","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/lometrexol-e1766","provider":"Absource Diagnostics","version":"1.0","type":"link"}