{"product_id":"lobetyolin-s9488","title":"Lobetyolin","description":"\u003cp\u003e\u003cstrong\u003eLobetyolin\u003c\/strong\u003e is an inhibitor of p53 used in studies of MAPK \/ ERK Signaling and Apoptosis. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and cell cycle models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting p53, Lobetyolin can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and caspase-associated cell-death signaling and survival decisions. This context is compatible with phosphorylation mapping, pathway-response, and growth assays and apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In apoptosis, cancer, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving p53\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling and Apoptosis\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in apoptosis, cancer, and cell cycle models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Lobetyolin is appropriate when a defined chemical perturbant is needed to connect p53 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809728373081,"sku":"S9488-5MG","price":144.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/S9488-Lobetyolin-chemical-structure.png?v=1776205185","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/lobetyolin-s9488","provider":"Absource Diagnostics","version":"1.0","type":"link"}