{"product_id":"linagliptin-gsk2118436-s3031","title":"Linagliptin (GSK2118436)","description":"\u003cp\u003e\u003cstrong\u003eLinagliptin (GSK2118436)\u003c\/strong\u003e is an inhibitor of DPP4 used in studies of Autophagy and Metabolic Signaling. In practice, this places the compound in experiments that measure autophagic flux, lysosomal turnover, and stress adaptation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in autophagy, endocrinology, and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting DPP4, Linagliptin (GSK2118436) can be used to examine autophagic flux, lysosomal turnover, and stress adaptation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The protease annotation adds relevance to protease-activity, cleavage, and substrate-processing assays, together with downstream-response mapping in the same experimental setting. In autophagy, endocrinology, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving DPP4\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Autophagy and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eProtease-activity, cleavage, and substrate-processing assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Linagliptin (GSK2118436) is appropriate when a defined chemical perturbant is needed to connect DPP4 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, endocrinology, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57808619733337,"sku":"S3031-5MG","price":105.0,"currency_code":"EUR","in_stock":true},{"title":"10 mg","offer_id":57808619766105,"sku":"S3031-10MG","price":166.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57808619798873,"sku":"S3031-100MG","price":274.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57808619831641,"sku":"S3031-1G","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57808619864409,"sku":"S3031-1ML\/DMSO","price":124.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Linagliptin-chemical-structure-s3031.gif?v=1776194335","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/linagliptin-gsk2118436-s3031","provider":"Absource Diagnostics","version":"1.0","type":"link"}