{"product_id":"le135-e7685","title":"LE135","description":"\u003cp\u003e\u003cstrong\u003eLE135\u003c\/strong\u003e is an antagonist of Retinoid Receptors and TRP Channels used in studies of Calcium Signaling. It is especially relevant in cell signaling, developmental biology, and endocrinology models, where defined compound exposure can be linked to calcium flux, excitability, and secretion-linked signaling.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Retinoid Receptors and TRP Channels, LE135 can be used to examine calcium flux, excitability, and secretion-linked signaling. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In cell signaling, developmental biology, and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Retinoid Receptors and TRP Channels\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Calcium Signaling\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, LE135 is appropriate when a defined chemical perturbant is needed to connect Retinoid Receptors and TRP Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling, developmental biology, and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Default Title","offer_id":57818635600217,"sku":"E7685","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e7685-le135-chemical-structure-tube.png?v=1776275821","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/le135-e7685","provider":"Absource Diagnostics","version":"1.0","type":"link"}