{"product_id":"lamp2-antibody-sc-f0997","title":"LAMP2 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eLAMP2 is a highly glycosylated type-1 lysosomal membrane protein that serves as a critical regulator of autophagy. In humans and mice, three isoforms of LAMP2 exist, while only a single isoform is present in rats. Mutations in the human LAMP2 gene cause Danon disease, a condition characterized by hypertrophic cardiomyopathy. Depending on the literature source, LAMP2 may also be discussed as LAMP-2 and CD107b.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, cytoplasmic vesicle, endosome, and lysosome, which can matter when signal is compared across treatments or changing cell states. Following LAMP2 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eLAMP2 is commonly interpreted in the context of oxidative stress research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cytoplasmic vesicle, and endosome, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, cytoplasmic vesicle, and endosome across matched conditions\u003c\/li\u003e\n\u003cli\u003eredox-associated shifts that may alter abundance, localization, or pathway coupling\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for LAMP2. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in LAMP2 reflect biology rather than handling. When interpreting LAMP2, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep LAMP2 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577586000217,"sku":"F0997-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577586032985,"sku":"F0997-100UL","price":369.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577586065753,"sku":"F0997-2X100UL","price":549.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0997-IF.png?v=1773599170","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/lamp2-antibody-sc-f0997","provider":"Absource Diagnostics","version":"1.0","type":"link"}