{"product_id":"kobe0065-s8303","title":"Kobe0065","description":"\u003cp\u003e\u003cstrong\u003eKobe0065\u003c\/strong\u003e is an inhibitor of RAF and CRAF used in studies of MAPK \/ ERK Signaling. It is especially relevant in cancer, cell cycle, and cell signaling models, where defined compound exposure can be linked to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting RAF and CRAF, Kobe0065 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell cycle, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving RAF and CRAF\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to MAPK \/ ERK Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Kobe0065 is appropriate when a defined chemical perturbant is needed to connect RAF and CRAF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell cycle, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57809598513497,"sku":"S8303-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"50 mg","offer_id":57809598546265,"sku":"S8303-50MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/kobe0065-chemical-structure-s8303.gif?v=1776202559","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/kobe0065-s8303","provider":"Absource Diagnostics","version":"1.0","type":"link"}