{"product_id":"kif3a-antibody-sc-f1414","title":"KIF3A Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eKinesin family member 3A (KIF3A) is a microtubule-oriented motor protein in the kinesin-2 family, crucial for intracellular transport and microtubule movement. KIF3A associates with microtubules during meiosis, and its depletion leads to oocyte maturation defects, activating the spindle assembly checkpoint and causing metaphase I arrest.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell projection, cilium, cytoplasm, and cytoskeleton, which can matter when signal is compared across treatments or changing cell states. Following KIF3A across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eKIF3A is commonly interpreted in the context of cell cycle and epigenetics research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell projection, cilium, and cytoplasm, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell projection, cilium, and cytoplasm across matched conditions\u003c\/li\u003e\n\u003cli\u003ecell-cycle linked differences in abundance, timing, or compartmental enrichment\u003c\/li\u003e\n\u003cli\u003elinks between target behavior and transcriptional or chromatin-state changes\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for KIF3A. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in KIF3A reflect biology rather than handling. When interpreting KIF3A, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep KIF3A trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577728278873,"sku":"F1414-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577728311641,"sku":"F1414-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577728344409,"sku":"F1414-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1414-wb.gif?v=1773599713","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/kif3a-antibody-sc-f1414","provider":"Absource Diagnostics","version":"1.0","type":"link"}