{"product_id":"il2r-antibody-sc-f3502","title":"IL-2Rα\/CD25 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eIL2R is a target of interest in many antibody-based workflows. The IL-2 receptor alpha chain (IL-2Rα, also known as CD25) is a 55-60 kDa glycoprotein that forms a crucial part of the interleukin-2 (IL-2) receptor complex, which also includes the IL-2Rβ (CD122) and common gamma (γc, CD132) chains. While IL-2Rα alone binds IL-2 with low affinity, its association with IL-2Rβ and γc creates a high-affinity receptor essential for effective IL-2 signaling and downstream immune responses. Depending on the literature source, IL2R may also be discussed as IL-2Ralpha\/CD25 and Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; p55; CD25; Il2ra; Il2r.\u003c\/p\u003e\u003cp\u003eReported cellular context includes membrane, which can matter when signal is compared across treatments or changing cell states. Following IL2R across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eIL2R is commonly interpreted in the context of immunology, developmental biology, and cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within membrane relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003econtext differences tied to immune-cell state, activation, or lineage composition\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for IL2R. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in IL2R reflect biology rather than handling. When interpreting IL2R, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep IL2R trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578027549017,"sku":"F3502-20UL","price":169.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578027581785,"sku":"F3502-100UL","price":399.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578027614553,"sku":"F3502-2X100UL","price":599.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3502-wb.gif?v=1773601265","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/il2r-antibody-sc-f3502","provider":"Absource Diagnostics","version":"1.0","type":"link"}