{"product_id":"idarubicin-hcl-s1228","title":"Idarubicin HCl","description":"\u003cp\u003e\u003cstrong\u003eIdarubicin HCl\u003c\/strong\u003e is a modulator of Topoisomerase used in studies of PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control in autophagy, cancer, and dna damage \/ repair models.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating Topoisomerase, Idarubicin HCl can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Topoisomerase\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Idarubicin HCl is appropriate when a defined chemical perturbant is needed to connect Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57805250986329,"sku":"S1228-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805251019097,"sku":"S1228-100MG","price":1562.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805251051865,"sku":"S1228-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Idarubicin-HCl-chemical-structure-S1228.gif?v=1776173163","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/idarubicin-hcl-s1228","provider":"Absource Diagnostics","version":"1.0","type":"link"}