{"product_id":"hmox1-antibody-sc-f3640","title":"Heme Oxygenase 1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eHMOX1 is a target of interest in many antibody-based workflows. Heme oxygenase-1 (HO-1) is both a stress-responsive protein and a metabolic enzyme that plays a vital role in maintaining cellular and tissue homeostasis. It also functions as a key regulator of immune responses, host defense mechanisms, and inflammation resolution. There are two primary isoforms of heme oxygenase: the inducible HO-1 and the constitutively expressed HO-2. Depending on the literature source, HMOX1 may also be discussed as Heme Oxygenase 1 and HO.\u003c\/p\u003e\u003cp\u003eReported cellular context includes endoplasmic reticulum and membrane, which can matter when signal is compared across treatments or changing cell states. Following HMOX1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eHMOX1 is commonly interpreted in the context of inflammation, cardiovascular, and metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans endoplasmic reticulum and membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between endoplasmic reticulum and membrane across matched conditions\u003c\/li\u003e\n\u003cli\u003eresponses associated with cytokine exposure, inflammatory tone, or tissue stress\u003c\/li\u003e\n\u003cli\u003echanges linked to vascular, contractile, or hemodynamic cell-state cues\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for HMOX1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in HMOX1 reflect biology rather than handling. When interpreting HMOX1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep HMOX1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578037772633,"sku":"F3640-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578037805401,"sku":"F3640-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578037838169,"sku":"F3640-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3640-IF.png?v=1773601363","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/hmox1-antibody-sc-f3640","provider":"Absource Diagnostics","version":"1.0","type":"link"}