{"product_id":"gsk778-ibet-bd1-s9683","title":"GSK778 (iBET-BD1)","description":"\u003cp\u003e\u003cstrong\u003eGSK778 (iBET-BD1)\u003c\/strong\u003e is an inhibitor of BET used in studies of Epigenetic Regulation. It is especially relevant in cancer and epigenetics models, where defined compound exposure can be linked to chromatin-state control, histone modification, and transcriptional regulation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting BET, GSK778 (iBET-BD1) can be used to examine chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving BET\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Epigenetic Regulation\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eChromatin, epigenetic, and gene-expression profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, GSK778 (iBET-BD1) is appropriate when a defined chemical perturbant is needed to connect BET with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"1 mg","offer_id":57809738727769,"sku":"S9683-1MG","price":254.0,"currency_code":"EUR","in_stock":true},{"title":"5 mg","offer_id":57809738760537,"sku":"S9683-5MG","price":763.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57809738793305,"sku":"S9683-1ML\/DMSO","price":842.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s9683-gsk778-ibet-bd1-chemical-structure.png?v=1776205208","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/gsk778-ibet-bd1-s9683","provider":"Absource Diagnostics","version":"1.0","type":"link"}