{"product_id":"gsk-3008348-hcl-e1558","title":"GSK-3008348 HCl","description":"\u003cp\u003e\u003cstrong\u003eGSK-3008348 HCl\u003c\/strong\u003e is an antagonist of Integrins used in studies of target-focused biology. It is especially relevant in angiogenesis and cancer models, where defined compound exposure can be linked to annotated target biology and downstream cellular responses.\u003c\/p\u003e\n\n\u003cp\u003eBy blocking Integrins, GSK-3008348 HCl can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with receptor-blockade and ligand-competition studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In angiogenesis and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Integrins\u003c\/li\u003e\n\u003cli\u003eReceptor-blockade and ligand-competition studies\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in angiogenesis and cancer models\u003c\/li\u003e\n\u003cli\u003eCombination studies with orthogonal perturbagens\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, GSK-3008348 HCl is appropriate when a defined chemical perturbant is needed to connect Integrins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804411765081,"sku":"E1558-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804411797849,"sku":"E1558-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804411830617,"sku":"E1558-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804411863385,"sku":"E1558-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E1558-GSK-3008348-HCl-chemical-structure.png?v=1776166999","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/gsk-3008348-hcl-e1558","provider":"Absource Diagnostics","version":"1.0","type":"link"}