{"product_id":"fxr2-antibody-sc-f1423","title":"FXR2 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eFragile X relative protein 2 (FXR2) is part of the fragile X mental retardation protein family, which includes FMRP, FXR1, and FXR2. These proteins are RNA-binding and associated with polyribosomes, with FMRP and FXR2 being particularly abundant in mammalian brains. FXR2 plays a crucial role in regulating neural stem cell proliferation and differentiation, particularly in the dentate gyrus (DG) of the brain.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm and synapse, which can matter when signal is compared across treatments or changing cell states. Following FXR2 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eFXR2 is commonly interpreted in the context of neuroscience, developmental biology, and stem cell biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm and synapse, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm and synapse across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003estate transitions between self-renewal, priming, and differentiation\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for FXR2. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in FXR2 reflect biology rather than handling. When interpreting FXR2, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep FXR2 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577732866393,"sku":"F1423-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577732899161,"sku":"F1423-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577732931929,"sku":"F1423-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1423-IF.png?v=1773599728","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/fxr2-antibody-sc-f1423","provider":"Absource Diagnostics","version":"1.0","type":"link"}