{"product_id":"fluoxetine-hydrochloride-ly-110140-s1333","title":"Fluoxetine Hydrochloride (LY-110140)","description":"\u003cp\u003e\u003cstrong\u003eFluoxetine Hydrochloride (LY-110140)\u003c\/strong\u003e is an inhibitor of 5-HT Receptors used in studies of GPCR Signaling and Neurotransmission. It is especially relevant in neuroscience models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting 5-HT Receptors, Fluoxetine Hydrochloride (LY-110140) can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving 5-HT Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to GPCR Signaling and Neurotransmission\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Fluoxetine Hydrochloride (LY-110140) is appropriate when a defined chemical perturbant is needed to connect 5-HT Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"25 mg","offer_id":57805270352217,"sku":"S1333-25MG","price":232.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805270384985,"sku":"S1333-100MG","price":390.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805270417753,"sku":"S1333-1G","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805270450521,"sku":"S1333-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Fluoxetine-chemical-structure-S1333.gif?v=1776173356","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/fluoxetine-hydrochloride-ly-110140-s1333","provider":"Absource Diagnostics","version":"1.0","type":"link"}