{"product_id":"fbp1-antibody-sc-f2476","title":"FBP1 Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eFructose-bisphosphatase 1 (FBP1) is a crucial rate-limiting enzyme in the gluconeogenesis pathway, primarily expressed in most cells and responsible for converting fructose-1,6-bisphosphate to fructose-6-phosphate, thereby regulating glucose production and inhibiting glycolysis. Structurally, FBP1 functions as a homotetramer and plays significant roles in glucose metabolism, including the synthesis of glycogen and polysaccharides. Depending on the literature source, FBP1 may also be discussed as FBPase 1.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm, cytosol, and nucleus, which can matter when signal is compared across treatments or changing cell states. Following FBP1 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eFBP1 is commonly interpreted in the context of cancer and metabolism research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm, cytosol, and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm, cytosol, and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003eresponses linked to nutrient status, mitochondrial state, or metabolic rewiring\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for FBP1. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in FBP1 reflect biology rather than handling. When interpreting FBP1, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep FBP1 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577953722713,"sku":"F2476-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577953755481,"sku":"F2476-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577953788249,"sku":"F2476-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F2476-IF.png?v=1773600443","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/fbp1-antibody-sc-f2476","provider":"Absource Diagnostics","version":"1.0","type":"link"}