{"product_id":"ewsr1-ews-antibody-sc-f3441","title":"EWSR1\/EWS Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eEWSR1\/EWS is a target of interest in many antibody-based workflows. EWSR1 (Ewing Sarcoma RNA-binding protein 1) is a multifunctional protein encoded by the EWSR1 gene located on chromosome 22q12. 2, playing critical roles in transcription, RNA splicing, and genomic stability. It contains an N-terminal transactivation domain (TAD) that interacts with transcription factors like TFIID and RNA polymerase II, an RNA-binding domain (RBD) for RNA attachment, and multiple low-complexity domains (LCDs) that facilitate dynamic interactions with nucleic acids and proteins. Depending on the literature source, EWSR1\/EWS may also be discussed as EWSR1\/EWS and EWS.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell membrane, cytoplasm, membrane, and nucleus, which can matter when signal is compared across treatments or changing cell states. Following EWSR1\/EWS across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eEWSR1\/EWS is commonly interpreted in the context of cancer and epigenetics research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell membrane, cytoplasm, and membrane, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell membrane, cytoplasm, and membrane across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003elinks between target behavior and transcriptional or chromatin-state changes\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for EWSR1\/EWS. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in EWSR1\/EWS reflect biology rather than handling. When interpreting EWSR1\/EWS, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep EWSR1\/EWS trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578023944537,"sku":"F3441-20UL","price":199.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578023977305,"sku":"F3441-100UL","price":489.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578024010073,"sku":"F3441-2X100UL","price":729.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3441-IF.png?v=1773601222","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ewsr1-ews-antibody-sc-f3441","provider":"Absource Diagnostics","version":"1.0","type":"link"}