{"product_id":"ertugliflozin-l-pyroglutamic-acid-s4431","title":"Ertugliflozin L-pyroglutamic acid","description":"\u003cp\u003e\u003cstrong\u003eErtugliflozin L-pyroglutamic acid\u003c\/strong\u003e is an inhibitor of SGLT and SGLT2 used in studies of Apoptosis and Metabolic Signaling. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions and metabolic regulation, energy sensing, and enzyme-linked homeostasis in apoptosis, cancer, and endocrinology models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting SGLT and SGLT2, Ertugliflozin L-pyroglutamic acid can be used to examine caspase-associated cell-death signaling and survival decisions and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The transporter annotation adds relevance to transport, uptake\/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving SGLT and SGLT2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis and Metabolic Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eTransport, uptake\/efflux, and permeability assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Ertugliflozin L-pyroglutamic acid is appropriate when a defined chemical perturbant is needed to connect SGLT and SGLT2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809045487961,"sku":"S4431-5MG","price":95.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809045520729,"sku":"S4431-25MG","price":285.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/s4431-ertugliflozin-l-pyroglutamic-acid-chemical-structure.gif?v=1776196442","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ertugliflozin-l-pyroglutamic-acid-s4431","provider":"Absource Diagnostics","version":"1.0","type":"link"}