{"product_id":"e7046-er-886406-s6649","title":"E7046 (ER-886406)","description":"\u003cp\u003e\u003cstrong\u003eE7046 (ER-886406)\u003c\/strong\u003e is an inhibitor of Prostaglandin Receptors used in studies of Immune Signaling and GPCR Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics in inflammation models.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Prostaglandin Receptors, E7046 (ER-886406) can be used to examine cytokine-mediated signaling and inflammatory effector responses and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Prostaglandin Receptors\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Immune Signaling and GPCR Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eGPCR pharmacology, ligand-binding, and signaling assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, E7046 (ER-886406) is appropriate when a defined chemical perturbant is needed to connect Prostaglandin Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57809402921305,"sku":"S6649-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57809402954073,"sku":"S6649-25MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e7046-chemical-structure-s6649.gif?v=1776200242","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/e7046-er-886406-s6649","provider":"Absource Diagnostics","version":"1.0","type":"link"}