{"product_id":"dx3-213b-e1139","title":"DX3-213B","description":"\u003cp\u003e\u003cstrong\u003eDX3-213B\u003c\/strong\u003e is an inhibitor of OXPHOS used in studies of Apoptosis. In practice, this places the compound in experiments that measure caspase-associated cell-death signaling and survival decisions in apoptosis, cancer, and metabolism models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting OXPHOS, DX3-213B can be used to examine caspase-associated cell-death signaling and survival decisions. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving OXPHOS\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to Apoptosis\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003ePathway-reporter and mechanistic-phenotyping studies\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, DX3-213B is appropriate when a defined chemical perturbant is needed to connect OXPHOS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804333678937,"sku":"E1139-5MG","price":293.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804333711705,"sku":"E1139-25MG","price":881.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1139-dx3-213b-chemical-structure.gif?v=1776166538","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/dx3-213b-e1139","provider":"Absource Diagnostics","version":"1.0","type":"link"}