{"product_id":"dpf2-req-antibody-sc-f3455","title":"DPF2\/REQ Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eDPF2\/REQ (DNA-binding Protein with a PHD Finger 2\/Requiem) is a multifunctional protein that plays a critical role in chromatin remodelling, gene regulation, and cellular processes such as development, differentiation, and immune response. As a member of the D4-protein family, DPF2 is characterized by its unique structural domains, including a C2H2 zinc finger domain and a C-terminal tandem plant homeodomain (PHD) finger. Depending on the literature source, DPF2\/REQ may also be discussed as DPF2\/REQ and DPF2\/BAF45D.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cytoplasm and nucleus, which can matter when signal is compared across treatments or changing cell states. Following DPF2\/REQ across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eDPF2\/REQ is commonly interpreted in the context of cancer, developmental biology, and epigenetics research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cytoplasm and nucleus, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cytoplasm and nucleus across matched conditions\u003c\/li\u003e\n\u003cli\u003echanges associated with proliferative state, oncogenic signaling, or treatment response\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003elinks between target behavior and transcriptional or chromatin-state changes\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for DPF2\/REQ. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in DPF2\/REQ reflect biology rather than handling. When interpreting DPF2\/REQ, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep DPF2\/REQ trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57578024632665,"sku":"F3455-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57578024665433,"sku":"F3455-100UL","price":329.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57578024698201,"sku":"F3455-2X100UL","price":489.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F3455-IF.png?v=1773601234","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/dpf2-req-antibody-sc-f3455","provider":"Absource Diagnostics","version":"1.0","type":"link"}