{"product_id":"doxorubicin-adriamycin-hydrochloride-s1208","title":"Doxorubicin (Adriamycin)Hydrochloride","description":"\u003cp\u003e\u003cstrong\u003eDoxorubicin (Adriamycin)Hydrochloride\u003c\/strong\u003e is an inhibitor of Topoisomerase and AMPK used in studies of PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs. It is especially relevant in autophagy, cancer, and dna damage \/ repair models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Topoisomerase and AMPK, Doxorubicin (Adriamycin)Hydrochloride can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In autophagy, cancer, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Topoisomerase and AMPK\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and DNA Damage Response and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eEnzyme-activity assays, substrate-conversion studies, and mechanism profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Doxorubicin (Adriamycin)Hydrochloride is appropriate when a defined chemical perturbant is needed to connect Topoisomerase and AMPK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, cancer, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"10 mg","offer_id":57805245579609,"sku":"S1208-10MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57805245612377,"sku":"S1208-25MG","price":272.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57805245645145,"sku":"S1208-100MG","price":468.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57805245677913,"sku":"S1208-1G","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 ml (10mM\/DMSO)","offer_id":57805245710681,"sku":"S1208-1ML\/DMSO","price":193.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/Adriamycin-Doxorubicin-chemical-structure-S1208.gif?v=1776173116","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/doxorubicin-adriamycin-hydrochloride-s1208","provider":"Absource Diagnostics","version":"1.0","type":"link"}