{"product_id":"dnajc3-antibody-sc-f1401","title":"p58IPK Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eDNAJC3 is a target of interest in many antibody-based workflows. p58IPK, a member of the heat shock protein (HSP) 40 family, possesses three distinct types of protein interaction domains: an N-terminal ER-targeting signal domain, a tetratricopeptide repeat (TPR) domain, and a C-terminal J domain. The N-terminal ER-targeting signal facilitates the translocation of p58IPK from the cytosol to the ER. Depending on the literature source, DNAJC3 may also be discussed as p58IPK.\u003c\/p\u003e\u003cp\u003eReported cellular context includes endoplasmic reticulum, which can matter when signal is compared across treatments or changing cell states. Following DNAJC3 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eDNAJC3 is commonly interpreted in the context of cell signaling research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans endoplasmic reticulum, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003esignal enrichment within endoplasmic reticulum relative to the broader cellular background\u003c\/li\u003e\n\u003cli\u003esignal-dependent shifts after ligand, inhibitor, or growth-factor perturbation\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003cli\u003etime-matched comparisons so changes reflect biology rather than handling or sampling drift\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for DNAJC3. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in DNAJC3 reflect biology rather than handling. When interpreting DNAJC3, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep DNAJC3 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577724248409,"sku":"F1401-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577724281177,"sku":"F1401-100UL","price":319.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577724313945,"sku":"F1401-2X100UL","price":479.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F1401-IHC1.jpg?v=1773599701","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/dnajc3-antibody-sc-f1401","provider":"Absource Diagnostics","version":"1.0","type":"link"}