{"product_id":"desmin-des-antibody-western-blot-validated","title":"Desmin (DES) Antibody - Western Blot Validated","description":"\u003ch2\u003eScientific Overview\u003c\/h2\u003e\n\u003cp\u003eTo connect mechanism with measurement, this antibody lets you characterize Desmin in pathway-driven studies. Desmin is a structural protein that interfaces with actin, microtubules, or associated adaptors. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.\u003c\/p\u003e\n\u003cp\u003eMonitoring Desmin alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eResearch Relevance\u003c\/h2\u003e\n\u003cp\u003eBecause cytoskeletal proteins can be abundant, interpretation benefits from attention to dynamic range and saturation. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.\u003c\/p\u003e\n\u003cp\u003eWhen cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood.\u003c\/p\u003e\n\u003cp\u003eWhen building a narrative around the target, it helps to track:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003edifferences across cell density or substrate stiffness\u003c\/li\u003e\n\u003cli\u003eremodeling after perturbation of polymerization or contractility\u003c\/li\u003e\n\u003cli\u003eassociation with junctional complexes or focal adhesions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplication-Specific Context\u003c\/h2\u003e\n\u003cp\u003eIf your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Desmin so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eChoose the denaturing-format format to study Desmin in a way that stays anchored to pathway logic.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58101726380377,"sku":"30041-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58101726413145,"sku":"30041-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58101726445913,"sku":"30041-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58101726478681,"sku":"30041-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58101726511449,"sku":"30041-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58101726544217,"sku":"30041-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/screenshot-2023-06-17-at-2.43.01-pm.png?v=1779281235","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/desmin-des-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}