{"product_id":"deg-77-e1413","title":"DEG-77","description":"\u003cp\u003e\u003cstrong\u003eDEG-77\u003c\/strong\u003e is a modulator of CK2 used in studies of kinase signaling. In practice, this places the compound in experiments that measure phosphorylation signaling, target engagement, and selectivity relationships in cancer, cell signaling, and metabolism models.\u003c\/p\u003e\n\n\u003cp\u003eBy modulating CK2, DEG-77 can be used to examine phosphorylation signaling, target engagement, and selectivity relationships. This target class is commonly examined through biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping. In cancer, cell signaling, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving CK2\u003c\/li\u003e\n\u003cli\u003eContext-dependent response profiling and mechanism comparison\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003cli\u003ePhenotypic profiling in cancer, cell signaling, and metabolism models\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, DEG-77 is appropriate when a defined chemical perturbant is needed to connect CK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804394037593,"sku":"E1413-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804394070361,"sku":"E1413-25MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1413-DEG-77-chemical-structure.png?v=1776166876","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/deg-77-e1413","provider":"Absource Diagnostics","version":"1.0","type":"link"}