{"product_id":"cu-ii-gtsm-e4674","title":"Cu (II)GTSM","description":"\u003cp\u003e\u003cstrong\u003eCu (II)GTSM\u003c\/strong\u003e is an inhibitor of GSK-3 used in studies of PI3K-Akt-mTOR Signaling and Wnt Signaling. It is especially relevant in cancer, cell signaling, and developmental biology models, where defined compound exposure can be linked to growth-factor signaling, survival control, and nutrient-sensing outputs and beta-catenin-dependent transcription and developmental signaling.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting GSK-3, Cu (II)GTSM can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs and beta-catenin-dependent transcription and developmental signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving GSK-3\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to PI3K-Akt-mTOR Signaling and Wnt Signaling\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Cu (II)GTSM is appropriate when a defined chemical perturbant is needed to connect GSK-3 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804927172953,"sku":"E4674-5MG","price":193.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804927205721,"sku":"E4674-25MG","price":488.0,"currency_code":"EUR","in_stock":true},{"title":"100 mg","offer_id":57804927238489,"sku":"E4674-100MG","price":953.0,"currency_code":"EUR","in_stock":true},{"title":"1 g","offer_id":57804927271257,"sku":"E4674-1G","price":2918.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/E4674-Cu-II-GTSM-chemical-structure.png?v=1776169960","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/cu-ii-gtsm-e4674","provider":"Absource Diagnostics","version":"1.0","type":"link"}