{"product_id":"ctnna2-antibody-sc-f0920","title":"α-N-Catenin Antibody","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\u003cp\u003eCTNNA2 is a target of interest in many antibody-based workflows. The cadherin-catenin complex comprises the cadherin adhesion receptor and associated catenins, including α-catenin, β-catenin, and p120 catenin. α-Catenin, an actin-binding protein, indirectly connects to cadherin via β-catenin, anchoring adherens junctions (AJs) to the actin cytoskeleton. In mammals, three α-catenin isoforms have been identified: αE-catenin, αN-catenin, and αT-catenin. Depending on the literature source, CTNNA2 may also be discussed as alpha-N-Catenin.\u003c\/p\u003e\u003cp\u003eReported cellular context includes cell junction, cell membrane, cell projection, and cytoplasm, which can matter when signal is compared across treatments or changing cell states. Following CTNNA2 across matched perturbations can help separate abundance effects from shifts in localization, complex assembly, or pathway state.\u003c\/p\u003e\u003ch2\u003eResearch Context\u003c\/h2\u003e\u003cp\u003eCTNNA2 is commonly interpreted in the context of neuroscience and developmental biology research, and readouts are often stronger when a study separates expression changes from compartment-level redistribution. When reported signal spans cell junction, cell membrane, and cell projection, a defined reference condition can make comparisons more interpretable across perturbations, passages, or replicate sets.\u003c\/p\u003e\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003eapparent redistribution between cell junction, cell membrane, and cell projection across matched conditions\u003c\/li\u003e\n\u003cli\u003ecompartment-specific patterns relevant to neuronal polarity, transport, or synaptic context\u003c\/li\u003e\n\u003cli\u003estage-dependent patterns during differentiation, morphogenesis, or lineage commitment\u003c\/li\u003e\n\u003cli\u003eco-patterning with orthogonal markers and control conditions that clarify pathway state\u003c\/li\u003e\n\u003c\/ul\u003e\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\u003cp\u003eIf your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior for CTNNA2. This can help when protocols evolve over time and the goal is to compare experiments using a stable reference workflow.\u003c\/p\u003e\u003cp\u003eStandardize sampling time, control choice, and downstream analysis thresholds so apparent differences in CTNNA2 reflect biology rather than handling. When interpreting CTNNA2, it is often useful to decide early whether the main question is overall abundance, compartmental enrichment, or context-dependent redistribution.\u003c\/p\u003e\u003cp\u003eFor multi-run studies, a shared reference condition can keep CTNNA2 trends easier to compare across datasets. That kind of consistency is especially helpful when follow-up work expands to new perturbations, model systems, or longitudinal collections.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"20 µl","offer_id":57577567781209,"sku":"F0920-20UL","price":149.0,"currency_code":"EUR","in_stock":true},{"title":"100 µl","offer_id":57577567813977,"sku":"F0920-100UL","price":319.0,"currency_code":"EUR","in_stock":true},{"title":"2 × 100 µl","offer_id":57577567846745,"sku":"F0920-2X100UL","price":479.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/F0920-IF.png?v=1773599098","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/ctnna2-antibody-sc-f0920","provider":"Absource Diagnostics","version":"1.0","type":"link"}