{"product_id":"csrm617-hydrochloride-e4312","title":"CSRM617 hydrochloride","description":"\u003cp\u003e\u003cstrong\u003eCSRM617 hydrochloride\u003c\/strong\u003e is an inhibitor of Androgen Receptor used in studies of DNA Damage Response and Apoptosis and related signaling programs. It is especially relevant in apoptosis, cancer, and dna damage \/ repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions.\u003c\/p\u003e\n\n\u003cp\u003eBy inhibiting Androgen Receptor, CSRM617 hydrochloride can be used to examine checkpoint activation, DNA repair, and genome-stability control and caspase-associated cell-death signaling and survival decisions. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and dna damage \/ repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving Androgen Receptor\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to DNA Damage Response and Apoptosis and related signaling programs\u003c\/li\u003e\n\u003cli\u003eConcentration-response inhibition and target-dependence studies\u003c\/li\u003e\n\u003cli\u003eReporter-gene, receptor-binding, and transcriptional assays\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, CSRM617 hydrochloride is appropriate when a defined chemical perturbant is needed to connect Androgen Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and dna damage \/ repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"5 mg","offer_id":57804882674009,"sku":"E4312-5MG","price":144.0,"currency_code":"EUR","in_stock":true},{"title":"25 mg","offer_id":57804882706777,"sku":"E4312-25MG","price":363.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e4312-CSRM617-hydrochloride-chemical-structure.png?v=1776169768","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/csrm617-hydrochloride-e4312","provider":"Absource Diagnostics","version":"1.0","type":"link"}