{"product_id":"coumermycin-a1-e1555","title":"Coumermycin A1","description":"\u003cp\u003e\u003cstrong\u003eCoumermycin A1\u003c\/strong\u003e is an activator of JAK2 used in studies of JAK-STAT Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to cytokine-responsive transcriptional signaling and immune regulation in cancer, cell signaling, and immunology models.\u003c\/p\u003e\n\n\u003cp\u003eBy activating JAK2, Coumermycin A1 can be used to examine cytokine-responsive transcriptional signaling and immune regulation. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.\u003c\/p\u003e\n\n\u003ch2\u003eResearch Applications\u003c\/h2\u003e\u003cul\u003e\n\u003cli\u003eTarget-focused assays involving JAK2\u003c\/li\u003e\n\u003cli\u003ePathway perturbation studies connected to JAK-STAT Signaling\u003c\/li\u003e\n\u003cli\u003eGain-of-function pathway-activation studies\u003c\/li\u003e\n\u003cli\u003eBiochemical kinase assays, phospho-signaling studies, and selectivity profiling\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003cp\u003eOverall, Coumermycin A1 is appropriate when a defined chemical perturbant is needed to connect JAK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.\u003c\/p\u003e","brand":"Selleck Chemicals","offers":[{"title":"Default Title","offer_id":57818424770905,"sku":"E1555","price":0.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/e1555-coumermycin-a1-chemical-structure-tube.png?v=1776275082","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/coumermycin-a1-e1555","provider":"Absource Diagnostics","version":"1.0","type":"link"}