{"product_id":"claudin-4-cldn4-antibody-western-blot-validated","title":"Claudin-4 (CLDN4) Antibody - Western Blot Validated","description":"\u003ch2\u003eProtein Function\u003c\/h2\u003e\n\u003cp\u003ePlan your comparisons around Claudin-4 and use this antibody to explore state-dependent differences. Claudin-4 is a structural regulator of intercellular boundaries and tissue architecture. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eMonitoring Claudin-4 alongside context markers can improve interpretation when phenotypes are subtle.\u003c\/p\u003e\n\u003ch2\u003eExperimental Applications\u003c\/h2\u003e\n\u003cp\u003eJunction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eMany workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.\u003c\/p\u003e\n\u003cp\u003eCommon experimental questions that benefit from target tracking include:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eWorkflow Perspective\u003c\/h2\u003e\n\u003cp\u003eIf your primary readout depends on denatured protein presentation, this option can streamline comparison across lanes and conditions. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Claudin-4 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eFor challenging targets, pairing Claudin-4 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.\u003c\/p\u003e\n\u003cp\u003eUse the denaturing-format option to keep Claudin-4 analysis aligned with planned contrasts and endpoints.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102377611609,"sku":"00204-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102377644377,"sku":"00204-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102377677145,"sku":"00204-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102377709913,"sku":"00204-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102377742681,"sku":"00204-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102377775449,"sku":"00204-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn4-cortex.jpg?v=1779283269","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/claudin-4-cldn4-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}