{"product_id":"claudin-18-cldn18-human-antibody-western-blot-validated","title":"Claudin-18 (CLDN18) (Human) Antibody - Western Blot Validated","description":"\u003ch2\u003eBiological Background\u003c\/h2\u003e\n\u003cp\u003eUse this antibody to examine Claudin-18 in your model system. Claudin-18 is a junctional protein that coordinates adhesion with cytoskeletal anchoring. Look for shifts in distribution that track with phenotype changes.\u003c\/p\u003e\n\u003cp\u003eIn some datasets and protocols, it is referenced by the gene symbol CLDN18.\u003c\/p\u003e\n\u003ch2\u003eUse in the Laboratory\u003c\/h2\u003e\n\u003cp\u003eJunction proteins are frequently analyzed during differentiation, stress responses, and changes in cell polarity. Pair measurements with orthogonal readouts when interpretation is sensitive to context.\u003c\/p\u003e\n\u003cp\u003eMany targets show context-dependent localization, so comparisons across matched conditions can reveal meaningful patterns.\u003c\/p\u003e\n\u003cp\u003eTo keep datasets interpretable, labs often document:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003cli\u003eco-localization patterns with cytoskeletal elements\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVersion Notes\u003c\/h2\u003e\n\u003cp\u003eFor size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Claudin-18 so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Claudin-18, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eChoose the denaturing-format option when you want Claudin-18 results aligned to your sample format.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102299296089,"sku":"00218H-WB-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102299328857,"sku":"00218H-WB-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102299361625,"sku":"00218H-WB-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102299394393,"sku":"00218H-WB-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102299427161,"sku":"00218H-WB-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102299459929,"sku":"00218H-WB-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn18-human.jpg?v=1779283155","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/claudin-18-cldn18-human-antibody-western-blot-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}