{"product_id":"claudin-16-cldn16-antibody-ffpe-validated","title":"Claudin-16 (CLDN16) Antibody - FFPE Validated","description":"\u003ch2\u003eAbout the Target\u003c\/h2\u003e\n\u003cp\u003ePlan your comparisons around Claudin-16 and use this antibody to evaluate state-dependent differences. Claudin-16 is a membrane-associated component that helps organize cell-cell contacts and polarity. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.\u003c\/p\u003e\n\u003cp\u003eFollowing Claudin-16 across perturbations can help separate expression effects from compartment shifts.\u003c\/p\u003e\n\u003ch2\u003eResearch Context\u003c\/h2\u003e\n\u003cp\u003eShifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Time course design can be decisive when regulation is transient or compartment dependent.\u003c\/p\u003e\n\u003cp\u003eConsider these angles when interpreting target-level changes:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003esubcellular redistribution at contact sites versus cytoplasm\u003c\/li\u003e\n\u003cli\u003echanges in complex assembly with scaffold or adaptor proteins\u003c\/li\u003e\n\u003cli\u003ecomparative profiling across cell states or perturbations\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eVariant Considerations\u003c\/h2\u003e\n\u003cp\u003eIn sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. This matters because epitope exposure and background can vary with preparation and extraction steps. Include controls that separate true target shifts from matrix or preparation effects.\u003c\/p\u003e\n\u003cp\u003eIf your study spans multiple model systems, it can help to define a shared reference condition for Claudin-16 so cross-sample contrasts stay meaningful.\u003c\/p\u003e\n\u003cp\u003eWhen interpreting Claudin-16, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.\u003c\/p\u003e\n\u003cp\u003eIntegrate the fixed-section version into your design so Claudin-16 signals can be interpreted alongside matched controls.\u003c\/p\u003e","brand":"BiCell Scientific","offers":[{"title":"50 µl \/ No Blocker","offer_id":58102320922969,"sku":"00216-FFPE-50UL","price":500.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 1 µg","offer_id":58102320955737,"sku":"00216-FFPE-50UL+1UG","price":569.0,"currency_code":"EUR","in_stock":true},{"title":"50 µl \/ 10 µg","offer_id":58102320988505,"sku":"00216-FFPE-50UL+10UG","price":619.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ No Blocker","offer_id":58102321021273,"sku":"00216-FFPE-200UL","price":1110.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 1 µg","offer_id":58102321054041,"sku":"00216-FFPE-200UL+1UG","price":1179.0,"currency_code":"EUR","in_stock":true},{"title":"200 µl \/ 10 µg","offer_id":58102321086809,"sku":"00216-FFPE-200UL+10UG","price":1229.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0923\/1011\/0553\/files\/cldn16-kidney_7860c238-be69-435a-b631-59634b4241ee.jpg?v=1779283194","url":"https:\/\/absource-diagnostics.myshopify.com\/products\/claudin-16-cldn16-antibody-ffpe-validated","provider":"Absource Diagnostics","version":"1.0","type":"link"}